Novel composite hydrogels representing interpenetrating polymeric networks (IPN) have been synthesized and consisted of Gluconacetobacter xylinus cellulose (GxC) and poly-1-vinyl-1,2,4-triazole (PVT) with Cu2⁺. The composite hydrogels’ mesostructure has been studied from 1.6 nm to 2.5 μm by small-angle and ultra-small-angle neutron scattering methods. It has been found that IPN complexes have three types of inhomogeneities: GxC, PVT, and PVT complex with Cu2⁺. The amount of the absorbed ions can be tuned as confirmed by electron paramagnetic spectroscopy. Besides, three hierarchy levels of GxC remained in the supramolecular structure of composite hydrogels. Reveling structure formation in these composite hydrogels is essential in fabricating hybrid polymeric materials for regenerative medicine, involving antibacterial or antifungal applications.
Novel biocompatible Cu2+-containing composite hydrogels based on bacterial cellulose and poly-1-vinyl-1,2,4-triazole
Smyslov, R.Y.; Kopitsa, G.P.; Gorshkova, Y.E.; Ezdakova, K. V.; Khripunov, A.K.; Migunova, A. V.; Tsvigun, N. V.; Korzhova, S.A.; Emel’yanov, A.I.; Pozdnyakov, A.S.
Smart Materials in Medicine. 2022.
DOI:10.1016/j.smaim.2022.05.002
Smart Materials in Medicine. 2022.
DOI:10.1016/j.smaim.2022.05.002
21 мая 2022